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Glycolysis

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0074 (pykA)  i ↓DNA182Variable: No limits set pyruvate kinase (EC 2.7.1.40)NLA0420; NMA0177; NMB0089; NMC0074
NEIS0199 (gapA)  i ↓DNA147Variable: No limits set glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12)NLA1650; NMA0062; NMB0207; NMC0199
NEIS0350 (fba)  i ↓DNA171Variable: No limits set fructose-1,6-bisphosphate aldolase (EC 4.1.2.13)NLA18140; NMA0587; NMB1869; NMC0350
NEIS0743 (pgm)  i ↓DNA184Variable: No limits set Phosphoglucomutase (EC 5.4.2.2)NLA14390; NMA1001; NMB0790; NMC0743 C. Kahler
NEIS1022 (fbp)  i ↓DNA117Variable: No limits set fructose-1,6-bisphosphatase (EC 3.1.3.11)NLA9450; NMA1259; NMB1060; NMC1022
NEIS1220 (eno)  i ↓DNA156Variable: No limits set phosphopyruvate hydratase (EC 4.2.1.11)NLA11220; NMA1495; NMB1285; NMC1220
NEIS1326 (pgi1)  i ↓DNA145Variable: No limits set glucose-6-phosphate isomerase (EC 5.3.1.9)NLA9300; NMA1599; NMB1388; NMC1326
NEIS1524 (gpm)  i ↓DNA151Variable: No limits set phosphoglycerate mutase (EC 5.4.2.1)NLA6840; NMA1801; NMB1604; NMC1524
NEIS1837 (pgi2)  i ↓DNA199Variable: No limits set glucose-6-phosphate isomerase 2 (EC 5.3.1.9)NLA3910; NMA2154; NMB0334; NMC1837
NEIS2137 (gapA2)  i ↓DNA147Variable: No limits set glyceraldehyde 3-phosphate dehydrogenase C (EC 1.2.1.12)NLA20510; NMA0246; NMB2159; NMC2137
NEIS2148 (pgk)  i ↓DNA165Variable: No limits set phosphoglycerate kinase (EC 2.7.2.3)NLA20620; NMA0257; NMB0010; NMC2148

TCA cycle

LocusDownloadTypeAllelesLength Full name/product Aliases
NEIS0620 (maeA)  i ↓DNA155Variable: No limits set malate oxidoreductase (EC 1.1.1.38)NMA0870; NMB0671; NMC0620
NEIS0897 (icd)  i ↓DNA240Variable: No limits set isocitrate dehydrogenase (NADP+) (EC 1.1.1.42)NLA13420; NMA1116; NMB0920; NMC0897
NEIS0924 (lpdA2)  i ↓DNA171Variable: No limits set dihydrolipoamide dehydrogenase (EC 1.8.1.4)NMA1142; NMB0947; NMC0924
NEIS0925 (sdhC)  i ↓DNA75Variable: No limits set succinate dehydrogenase cytochrome B subunit (EC 1.3.99.1)NLA13120; NMA1143; NMB0948; NMC0925
NEIS0926 (sdhD)  i ↓DNA89Variable: No limits set succinate dehydrogenase hydrophobic membrane anchor protein (EC 1.3.99.1)NLA13110; NMA1144; NMB0949; NMC0926
NEIS0927 (sdhA)  i ↓DNA167Variable: No limits set succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)NLA13100; NMA1145; NMB0950; NMC0927
NEIS0928 (sdhB)  i ↓DNA122Variable: No limits set succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)NLA13090; NMA1146; NMB0951; NMC0928
NEIS0930 (gltA)  i ↓DNA140Variable: No limits set citrate synthase (EC 2.3.3.1)NLA13070; NMA1148; NMB0954; NMC0930
NEIS0931 (sucA)  i ↓DNA222Variable: No limits set 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)NLA13060; NMA1149; NMB0955; NMC0931
NEIS0932 (sucB)  i ↓DNA151Variable: No limits set dihydrolipoamide succinyltransferase E2 component (EC 2.3.1.61)NLA13050; NMA1150; NMB0956; NMC0932
NEIS0935 (sucC)  i ↓DNA140Variable: No limits set succinyl-CoA synthetase subunit beta (EC 6.2.1.5)NLA13020; NMA1153; NMB0959; NMC0935
NEIS0936 (sucD)  i ↓DNA128Variable: No limits set succinyl-CoA synthetase subunit alpha (EC 6.2.1.5)NLA13010; NMA1154; NMB0960; NMC0936
NEIS1396 (fumC)  i ↓DNA206Variable: No limits set fumarate hydratase class II (EC 4.2.1.2)NLA8680; NMA1670; NMB1458; NMC1396
NEIS1492 (acnB)  i ↓DNA176Variable: No limits set aconitate hydratase 2 (EC 4.2.1.3)NLA7110; NMA1761; NMB1572; NMC1492
NEIS1534 (fumA)  i ↓DNA173Variable: No limits set fumarate hydratase class I (EC 4.2.1.2)NMA1812; NMB1613; NMC1534
NEIS1729 (acnA)  i ↓DNA171Variable: No limits set aconitate hydratase 1 (EC 4.2.1.3)NMA2052; NMB0433; NMC1729

Pyruvate dehydrogenase complex

LocusDownloadTypeAllelesLength Full name/product Aliases
NEIS1278 (pdhC)  i ↓DNA171Variable: (2664 min; 2679 max) pyruvate dehydrogenase (EC 1.2.4.1)NLA11750; NMA1554; NMB1341; NMC1278
NEIS1279 (aceF)  i ↓DNA149Variable: (1563 min; 1641 max) dihydrolipoamide acetyltransferase (EC 2.3.1.12)NLA11760; NMA1555; NMB1342; NMC1279
NEIS1280 (lpd)  i ↓DNA152Variable: (1758 min; 1818 max) dihydrolipoamide dehydrogenase (EC 1.8.1.4)NMC1280

ADP-heptose biosynthesis

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0769 (hldA)  i ↓DNA88Variable: No limits set D-beta-D-heptose-7-phosphate kinaseNMB0825; NMC0769; rfaE C. Kahler
NEIS0773 (hldD)  i ↓DNA141Variable: No limits set ADP-D-beta-D heptose epimeraseNMB0828; NMC0773 C. Kahler
NEIS2014 (gmhB)  i ↓DNA90Variable: No limits set D-alpha,beta,D-Heptose 1,7 bisphosphate phosphataseNMB2033; NMC2014 C. Kahler
NEIS2055 (hldC)  i ↓DNA84Variable: No limits set D-beta-D-heptose-1-phosphate adenylyltransferase NMB2076; NMC2055 C. Kahler
NEIS2070 (gmhA)  i ↓DNA81Variable: No limits set sedoheptulose-7-phosphate isomeraseNMB2090; NMC2070 C. Kahler

LOS inner core transferases

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0291 (lot)  i ↓DNA106Variable: No limits set LOS O-acetyltransferaseNMA2202; NMC0291 C. Kahler
NEIS1456 (rfaF)  i ↓DNA95Variable: No limits set Heptosyltransferase IINMB1527; NMC1456 C. Kahler
NEIS1619 (rfaK)  i ↓DNA65Variable: No limits set alpha-1,2 N-acetylglucosamine transferaseNMB1705; NMC1619 C. Kahler
NEIS1986 (lpt3)  i ↓DNA70Variable: No limits set LOS O-3 PEA transferaseNMB2010; NMC1986 C. Kahler
NEIS2011 (lgtG)  i ↓DNA53Variable: No limits set O-3 linked glucosyltransferaseNMC2011 C. Kahler
NEIS2012 (lpt6)  i ↓DNA29Variable: No limits set O-6 PEA LOS transferaseNMA0408; NMC2012 C. Kahler
NEIS2134 (rfaC)  i ↓DNA87Variable: No limits set Heptosyl transferase INMB2156; NMC2134 C. Kahler

LOS alpha chain transferases

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0899 (lst)  i ↓DNA92Variable: No limits set alpha-2,3-sialyltransferaseNMB0922; NMC0899 C. Kahler
NEIS1618 (lgtF)  i ↓DNA59Variable: No limits set beta-1,4 glucosyltransferaseNMB1704; NMC1618 C. Kahler
NEIS1900 (lgtE)  i ↓DNA185Variable: No limits set lacto-N-neotetraose biosynthesis glycosyl transferaseNMB1926; NMC1900 C. Kahler
NEIS1901 (lgtB)  i ↓DNA189Variable: No limits set lacto-N-neotetraose biosynthesis glycosyl transferaseNMB1928; NMC1901 C. Kahler
NEIS1902 (lgtA)  i ↓DNA80Variable: No limits set lacto-N-neotetraose biosynthesis glycosyl transferaseNMB1929; NMC1902 C. Kahler
NEIS2154 (lgtC)  i ↓DNA20Variable: No limits set LOS glycosyltransferase C. Kahler
NEIS2155 (lgtD)  i ↓DNA110Variable: No limits set C. Kahler

UDP-glucose and UDP-galactose biosynthesis

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0048 (galE)  i ↓DNA161Variable: No limits set UDP-glucose epimeraseNMA0203; NMB0064; NMC0048 C. Kahler
NEIS0743 (pgm)  i ↓DNA184Variable: No limits set Phosphoglucomutase (EC 5.4.2.2)NLA14390; NMA1001; NMB0790; NMC0743 C. Kahler

UDP-GlcNAc synthesis

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0015 (glmU)  i ↓DNA178Variable: No limits set UDP-N-acetylglucosamine pyrophosphorylaseNMB0038; NMC0015 C. Kahler

Lipid A biosynthesis: acyltransferases

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0168 (lpxA)  i ↓DNA134Variable: No limits set UDP-N-acetylglucosamine acyltransferaseNMB0178; NMC0168 A. van der Ende, P. van der Ley
NEIS0171 (lpxD)  i ↓DNA131Variable: No limits set UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-)NMB0180; NMC0171 A. van der Ende, P. van der Ley
NEIS0421 (lpxL2)  i ↓DNA68Variable: No limits set lipid A biosynthesis lauroyl transferaseNMB1801; NMC0421 A. van der Ende, P. van der Ley
NEIS1351 (lpxL)  i ↓DNA101Variable: No limits set lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-)NMB1418; NMC1351; htrB; lpxL1; msbB A. van der Ende, P. van der Ley

Lipid A biosynthesis: other

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0001 (lpxC)  i ↓DNA204Variable: No limits set UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (EC 3.5.1.-)NMB0017; NMC0001; envA A. van der Ende, P. van der Ley
NEIS0191 (lpxB)  i ↓DNA130Variable: No limits set lipid-A-disaccharide synthase (EC 2.4.1.182)NMB0199; NMC0191 A. van der Ende, P. van der Ley
NEIS0483 (lpxH)  i ↓DNA97Variable: No limits set UDP-2,3-diacylglucosamine hydrolaseNMB0544; NMC0483 A. van der Ende, P. van der Ley
NEIS0621 (lpxK)  i ↓DNA82Variable: No limits set tetraacyldisaccharide 4'-kinase (EC 2.7.1.130)NMB0672; NMC0621 A. van der Ende, P. van der Ley
NEIS1553 (lptA)  i ↓DNA131Variable: No limits set Lipid A phosphoethanolamine transferaseNMB1638; NMC1553 A. van der Ende, P. van der Ley

Kdo addition

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0624 (kdsB)  i ↓DNA135Variable: No limits set 3-deoxy-manno-octulosonate cytidylyltransferaseNMB0675; NMC0624 A. van der Ende, P. van der Ley
NEIS1218 (kdsA)  i ↓DNA90Variable: No limits set 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55)NMB1283; NMC1218 A. van der Ende, P. van der Ley
NEIS1815 (kdsC)  i ↓DNA92Variable: No limits set 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, KDO 8-P phosphatase (EC 3.1.3.45)NMB0353; NMC1815 A. van der Ende, P. van der Ley
NEIS1816 (kpsF)  i ↓DNA143Variable: No limits set arabinose-5-phosphate isomerase (EC 5.3.1.13)NMB0352; NMC1816 A. van der Ende, P. van der Ley
NEIS2152 (kdtA)  i ↓DNA121Variable: No limits set 3-deoxy-D-manno-octulosonic-acid transferaseNMB0014; NMC2152 A. van der Ende, P. van der Ley

LOS transport/export

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0304 (msbA)  i ↓DNA115Variable: No limits set Lipid A export ATP-binding/permease protein (IM)NMB1919; NMC0304 A. van der Ende, P. van der Ley
NEIS0657 (rlpB)  i ↓DNA33Variable: No limits set NMB0707; NMC0657 A. van der Ende, P. van der Ley
NEIS1812 (yhbG)  i ↓DNA103Variable: No limits set lipopolysaccharide ABC transporterNMB0356; NMC1812; lptB A. van der Ende, P. van der Ley
NEIS1813 (ostA)  i ↓DNA71Variable: No limits set NMB0355; NMC1813 A. van der Ende, P. van der Ley
NEIS1814 (lptC)  i ↓DNA92Variable: No limits set lipopolysaccharide export system protein (OM)NMB0354; NMC1814; imp A. van der Ende, P. van der Ley

Purine metabolism

LocusDownloadTypeAllelesLength Full name/product Aliases Curator(s)
NEIS0074 (pykA)  i ↓DNA182Variable: No limits set pyruvate kinase (EC 2.7.1.40)NLA0420; NMA0177; NMB0089; NMC0074
NEIS0123  i ↓DNA145Variable: No limits set DNA-directed RNA polymerase subunit betaNMC0123
NEIS0124  i ↓DNA157Variable: No limits set DNA-directed RNA polymerase subunit beta'NMC0124
NEIS0158  i ↓DNA77Variable: No limits set DNA-directed RNA polymerase subunit alphaNMC0158
NEIS0290  i ↓DNA110Variable: No limits set adenylosuccinate lyaseNMC0290
NEIS0303  i ↓DNA114Variable: No limits set GMP synthaseNMC0303
NEIS0321 (dnaN)  i ↓DNA129Variable: No limits set DNA polymerase III subunit beta NMC0321
NEIS0389  i ↓DNA182Variable: No limits set DNA polymerase III, alpha subunitNMC0389
NEIS0582  i ↓DNA87Variable: No limits set putative deoxyribonucleotide triphosphate pyrophosphataseNMC0582
NEIS0641  i ↓DNA107Variable: No limits set amidophosphoribosyltransferaseNMC0641
NEIS0658  i ↓DNA135Variable: No limits set DNA polymerase III subunit deltaNMC0658
NEIS0709  i ↓DNA116Variable: No limits set phosphoribosylaminoimidazole-succinocarboxamide synthaseNMC0709
NEIS0710  i ↓DNA176Variable: No limits set polynucleotide phosphorylase/polyadenylaseNMC0710
NEIS0722  i ↓DNA117Variable: No limits set DNA polymerase III subunit delta'NMC0722
NEIS0743 (pgm)  i ↓DNA184Variable: No limits set Phosphoglucomutase (EC 5.4.2.2)NLA14390; NMA1001; NMB0790; NMC0743 C. Kahler
NEIS0765  i ↓DNA131Variable: No limits set adenylosuccinate synthetaseNMC0765
NEIS0767 (adk)  i ↓DNA108Variable: No limits set adenylate kinaseNMC0767
NEIS0816  i ↓DNA117Variable: No limits set ribose-phosphate pyrophosphokinaseNMC0816
NEIS0963  i ↓DNA153Variable: No limits set bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolaseNMC0963
NEIS1011  i ↓DNA143Variable: No limits set phosphoribosylaminoimidazole carboxylase ATPase subunitNMC1011
NEIS1103  i ↓DNA167Variable: No limits set inosine 5'-monophosphate dehydrogenaseNMC1103
NEIS1152  i ↓DNA115Variable: No limits set phosphoribosylaminoimidazole synthetaseNMC1152
NEIS1223  i ↓DNA128Variable: No limits set ribonucleotide-diphosphate reductase subunit betaNMC1223
NEIS1226  i ↓DNA145Variable: No limits set ribonucleotide-diphosphate reductase subunit alphaNMC1226
NEIS1374  i ↓DNA94Variable: No limits set phosphoribosylaminoimidazole carboxylase catalytic subunitNMC1374
NEIS1379  i ↓DNA146Variable: No limits set DNA polymerase III subunits gamma and tauNMC1379
NEIS1405  i ↓DNA154Variable: No limits set exopolyphosphataseNMC1405
NEIS1419  i ↓DNA108Variable: No limits set stationary phase survival protein SurENMC1419
NEIS1486  i ↓DNA128Variable: No limits set phosphoribosylglycinamide transformylaseNMC1486
NEIS1488  i ↓DNA88Variable: No limits set DNA polymerase III chi subunitNMC1488
NEIS1577  i ↓DNA120Variable: No limits set guanosine-3',5'-bis(diphosphate) 3'-pyrophophohydrolaseNMC1577
NEIS1578  i ↓DNA62Variable: No limits set DNA-directed RNA polymerase omega chainNMC1578
NEIS1579  i ↓DNA105Variable: No limits set guanylate kinaseNMC1579
NEIS1580  i ↓DNA69Variable: No limits set adenine phosphoribosyltransferaseNMC1580
NEIS1655  i ↓DNA108Variable: No limits set GTP pyrophosphokinaseNMC1655
NEIS1957  i ↓DNA167Variable: No limits set DNA polymerase INMC1957
NEIS1972  i ↓DNA156Variable: No limits set phosphoribosylformylglycinamidine synthaseNMC1972
NEIS2027  i ↓DNA74Variable: No limits set hypoxanthine-guanine phosphoribosyltransferaseNMC2027
NEIS2129  i ↓DNA150Variable: No limits set phosphoribosylamine--glycine ligaseNMC2129

Pyrimidine metabolism

LocusDownloadTypeAllelesLength Full name/product Aliases
NEIS0098  i ↓DNA135Variable: No limits set aspartate carbamoyltransferase catalytic subunitNMC0098
NEIS0123  i ↓DNA145Variable: No limits set DNA-directed RNA polymerase subunit betaNMC0123
NEIS0124  i ↓DNA157Variable: No limits set DNA-directed RNA polymerase subunit beta'NMC0124
NEIS0158  i ↓DNA77Variable: No limits set DNA-directed RNA polymerase subunit alphaNMC0158
NEIS0218  i ↓DNA91Variable: No limits set dihydroorotate dehydrogenase 2NMC0218
NEIS0321 (dnaN)  i ↓DNA129Variable: No limits set DNA polymerase III subunit beta NMC0321
NEIS0345  i ↓DNA87Variable: No limits set orotate phosphoribosyltransferaseNMC0345
NEIS0363 (carB)  i ↓DNA238Variable: No limits set carbamoyl phosphate synthase large subunit (EC 6.3.5.5)NMC0363
NEIS0370  i ↓DNA152Variable: No limits set carbamoyl phosphate synthase small subunitNMC0370
NEIS0389  i ↓DNA182Variable: No limits set DNA polymerase III, alpha subunitNMC0389
NEIS0582  i ↓DNA87Variable: No limits set putative deoxyribonucleotide triphosphate pyrophosphataseNMC0582
NEIS0619  i ↓DNA69Variable: No limits set thymidylate kinaseNMC0619
NEIS0633  i ↓DNA89Variable: No limits set dihydroorotaseNMC0633
NEIS0658  i ↓DNA135Variable: No limits set DNA polymerase III subunit deltaNMC0658
NEIS0710  i ↓DNA176Variable: No limits set polynucleotide phosphorylase/polyadenylaseNMC0710
NEIS0722  i ↓DNA117Variable: No limits set DNA polymerase III subunit delta'NMC0722
NEIS0727  i ↓DNA102Variable: No limits set uracil phosphoribosyltransferaseNMC0727
NEIS0768  i ↓DNA100Variable: No limits set orotidine 5'-phosphate decarboxylaseNMC0768
NEIS0789  i ↓DNA100Variable: No limits set deoxycytidine triphosphate deaminaseNMC0789
NEIS0833  i ↓DNA136Variable: No limits set deoxyuridine 5'-triphosphate nucleotidohydrolaseNMC0833
NEIS0911  i ↓DNA109Variable: No limits set putative cytosine deaminaseNMC0911
NEIS1223  i ↓DNA128Variable: No limits set ribonucleotide-diphosphate reductase subunit betaNMC1223
NEIS1226  i ↓DNA145Variable: No limits set ribonucleotide-diphosphate reductase subunit alphaNMC1226
NEIS1261  i ↓DNA98Variable: No limits set thioredoxin reductaseNMC1261
NEIS1379  i ↓DNA146Variable: No limits set DNA polymerase III subunits gamma and tauNMC1379
NEIS1419  i ↓DNA108Variable: No limits set stationary phase survival protein SurENMC1419
NEIS1471  i ↓DNA164Variable: No limits set CTP synthetaseNMC1471
NEIS1488  i ↓DNA88Variable: No limits set DNA polymerase III chi subunitNMC1488
NEIS1578  i ↓DNA62Variable: No limits set DNA-directed RNA polymerase omega chainNMC1578
NEIS1624  i ↓DNA132Variable: No limits set thymidylate synthaseNMC1624
NEIS1957  i ↓DNA167Variable: No limits set DNA polymerase INMC1957
NEIS2082  i ↓DNA121Variable: No limits set uridylate kinaseNMC2082

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